Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003s009 | SSR New Investigator Lecture | SRF2016

Epigenetics of the male germline from stem cells to sperm

Namekawa Satoshi H.

The cellular identity of germ cells, the only heritable lineage to the next generation, is distinct from those of somatic lineages. The somatic program is largely suppressed in male germ cells which retain unique cellular identity, passed on to the compacted sperm, and give rise to a totipotent zygote after fertilization. We recently demonstrated that a few thousand genes commonly expressed in somatic lineages and spermatogenesis-progenitor cells (termed somatic/progenitor gen...